Definition of phosphate 1a(1) : a salt or ester of a phosphoric acid. (2) : the trivalent anion PO43− derived from phosphoric acid H3PO4. b : an organic compound of phosphoric acid in which the acid group is bound to nitrogen or a carboxyl group in a way that permits useful energy to be released (as in metabolism)
What is a phosphate in DNA?
A phosphate backbone is the portion of the DNA double helix that provides structural support to the molecule. DNA consists of two strands that wind around each other like a twisted ladder. Each strand has a backbone made of alternating sugar (deoxyribose) and phosphate groups.
Why is phosphate important in biology?
Phosphate is necessary for the formation of bone and teeth. Phosphate is also used as a building block for several important substances, including those used by the cell for energy, cell membranes, and DNA (deoxyribonucleic acid). The body obtains phosphate from foods and excretes it in urine and sometimes stool.
What is phosphate used for?
Today most of our phosphorus comes from phosphate rock that is mined around the world, and then converted to phosphoric acid. Fifty million tonnes are made every year and it has multiple uses. It is used to make fertilisers, animal feeds, rust removers, corrosion preventers, and even dishwasher tablets.
What is another name for phosphate?
In this page you can discover 18 synonyms, antonyms, idiomatic expressions, and related words for phosphate, like: ammonium, ammonia, inorganic phosphate, orthophosphate, sulphate, chloride, phosphorus, triose, tricalcium, sulfate and nitrate.
What is an example of phosphate?
Codeine phosphate. Effervescent sodium phosphate. Oleandomycin phosphate. Utp-glucose-1-phosphate uridylyltransferase.
Is phosphate in DNA or RNA?
Both DNA and RNA contain one, two or three phosphate groups, attached to the 5′ carbon of the pentose sugar.
Where is phosphate found in the body?
Of the total phosphate in the body, 85% is n the bones and teeth,1% in the extracellular fluid and the remaining 14% is distributed in other tissues where it is an important constituent of cell membranes, nucleic acids, high energy phosphate esters (ATP) and intracellular signaling proteins.
What is phosphate made of?
In their natural form phosphates are chemical compounds made of oxygen and phosphorus. If you’ve taken biology or chemistry classes, you might remember phosphorus from the Periodic Table of Elements. Phosphates are minerals our bodies need to maintain healthy teeth, bones, heart function, muscles and blood vessels.
What is the role of phosphate in metabolism?
Inorganic phosphate (Pi) is essential for various cellular metabolism and skeletal mineralization. It is an essential part of nucleic acids and the cell membrane, serves as an important mediator of intracellular signaling, and regulates protein activity.
What causes low phosphate levels?
Hypophosphataemia is the term used to describe low levels of phosphate in the blood. It is most commonly caused by hyperparathyroidism and vitamin D deficiency.
Is phosphate a potassium?
Phosphorus is a naturally occurring substance that is important in every cell in the body. The majority of phosphorus in the body is found in the bones. The potassium and sodium salt forms of phosphorus are called phosphates.
Who produces phosphate?
While nearly 30 countries produce phosphate rock, China, the United States and Morocco are the largest producers, together accounting for two-thirds of world production. Morocco alone accounts for more than 30 percent of global exports.
What foods contain phosphate?
Phosphorus can be found in foods (organic phosphorus) and is naturally found in protein-rich foods such as meats, poultry, fish, nuts, beans and dairy products.
Where does the phosphate come from?
The phosphate comes from sediment that was deposited in layers on the sea floor. The phosphate rich sediments are believed to have formed from precipitation of phosphate from seawater along with the skeletons and waste products of creatures living in the seas.
How is phosphate produced?
Phosphate fertilizers are produced by adding acid to ground or pulverized phosphate rock. If sulfuric acid is used, single or normal, phosphate (SSP) is produced, with a phosphorus content of 16–21% as phosphorous pentoxide (P2O5).
What are the three types of phosphates?
Phosphates exist in three forms: orthophosphate, metaphosphate (or polyphosphate) and organically-bound phosphate; each compound contains phosphorous in a different chemical arrangement.
How many phosphates are in DNA?
A free, unincorporated nucleotide usually exists in a triphosphate form; that is, it contains a chain of three phosphates. In DNA, however, it loses two of these phosphate groups, so that only one phosphate is incorporated into a strand of DNA.
Does DNA have phosphate?
In double-stranded DNA, the molecular double-helix shape is formed by two linear sugar-phosphate backbones that run opposite each other and twist together in a helical shape. The sugar-phosphate backbone is negatively charged and hydrophilic, which allows the DNA backbone to form bonds with water.
Is phosphate a sugar?
Sugar phosphates (sugars that have added or substituted phosphate groups) are often used in biological systems to store or transfer energy. They also form the backbone for DNA and RNA. Sugar phosphate backbone geometry is altered in the vicinity of the modified nucleotides.
What happens if your phosphate levels are low?
Symptoms of phosphorus deficiency include loss of appetite, anxiety, bone pain, fragile bones, stiff joints, fatigue, irregular breathing, irritability, numbness, weakness, and weight change. In children, decreased growth and poor bone and tooth development may occur.
What happens if you have too much phosphate in your body?
Too much phosphate can be toxic. An excess of the mineral can cause diarrhea, as well as a hardening of organs and soft tissue. High levels of phosphorus can affect your body’s ability to effectively use other minerals, such as iron, calcium, magnesium, and zinc.
What happens when phosphorus is too high?
High phosphorus often does not cause symptoms itself. However, extra phosphorus in your blood can remove calcium from your bones and other parts of your body, leading to low calcium (also called hypocalcemia). Low calcium does cause symptoms, such as: Muscle cramps.
What are phosphates in the body?
Phosphate is a chemical that contains the mineral phosphorus. Phosphates are essential for the production of energy, muscle and nerve function, and bone growth.
What are the two types of phosphates?
There are too many variations of phosphates to name, so let’s divide them into two main subcategories: organic and inorganic phosphates.