What is an activator cell biology?

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A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.

What is an example of an activator in biology?

One example of an activator is the protein CAP. In the presence of cAMP, CAP binds to the promoter and increases RNA polymerase activity. In the absence of cAMP, CAP does not bind to the promoter. Transcription occurs at a low rate.

What is an activator definition?

Definition of ‘activator’ 1. a thing or person that activates. Chemistry. a substance used to induce or accelerate a chemical reaction.

What are activators and enhancers?

Transcription factors that are activators boost a gene’s transcription. Repressors decrease transcription. Groups of transcription factor binding sites called enhancers and silencers can turn a gene on/off in specific parts of the body.

What is the function of an activator quizlet?

The main function of activators and co-activators is to attract position, and modify GTFs and RNA Pol 2 at core promoter. They accomplish this by: acting directly on the transcription initiation machinery, DNA bending (architectural proteins) – allows activators to function at a distance through DNA looping.

What are activators and repressors?

According to the conventional wisdom, transcription factors are typically classified as “activators” or “repressors”. Activators recruit coactivators, resulting in gene activation, while repressors recruit corepressors, leading to transcriptional repression.

What are types of activators in enzymes?

Some examples of enzyme activators are calcium and magnesium ions, calmodulin, EDTA, EGTA, fructose 2,6-bisphosphate, hexokinase-1, and, glucokinase while some examples of enzyme inhibitors are N-ethylmaleimide, DFMO, DFP, and most of the pharmaceutical drugs.

What is activator and inhibitor?

Molecules that increase the activity of an enzyme are called activators, while molecules that decrease the activity of an enzyme are called inhibitors.

What are the two types of enzyme activators?

Enzymatic activators are molecules that can increase the activity of an enzyme. Examples of enzymatic activators are cofactors and coenzymes.

What is another term for activator?

activating agent, catalyst, sensitiser, accelerator, sensitizer.

What does inhibitor mean in biology?

In enzymology, a compound, or even a macromolecule, that blocks the action of an enzyme by reversible attachment in such a way as to prevent binding by the substrate (competitive inhibition), or by prevention of the reaction even if the substrate can still bind (non-competitive inhibition).

Is Activatory a word?

Activatory definition That acts as an activator.

Is activator the same as promoter?

An activator facilitates the upregulation of the transcription process by binding to enhancers, while promoter is the site at which RNA polymerase binds, and transcription initiation takes place, and repressor downregulates transcription by binding to silencers.

What is an enhancer in biology?

Enhancers are classically defined as cis-acting DNA sequences that can increase the transcription of genes. They generally function independently of orientation and at various distances from their target promoter (or promoters).

Is an enhancer and an activator the same thing?

An enhancer is a DNA sequence that promotes transcription. Each enhancer is made up of short DNA sequences called distal control elements. Activators bound to the distal control elements interact with mediator proteins and transcription factors.

Why is regulation of gene expression important quizlet?

We regulate gene expression because transcription and translation take lots of energy so we need it. And it would be a waste of energy to make all proteins in all cells.

What is the function of Dideoxynucleotides in Sanger DNA sequencing quizlet?

What is the function of dideoxynucleotides in Sanger DNA sequencing? They act as primers for DNA polymerase.

What has to happen before transcription can start in eukaryotic cells?

Before transcription can take place, the DNA double helix must unwind near the gene that is getting transcribed. The region of opened-up DNA is called a transcription bubble. In transcription, a region of DNA opens up.

What is a repressor in biology?

​Repressor A repressor, as related to genomics, is a protein that inhibits the expression of one or more genes. The repressor protein works by binding to the promoter region of the gene(s), which prevents the production of messenger RNA (mRNA).

Where do activator proteins bind?

Activator proteins bind to regulatory sites on DNA nearby to promoter regions that act as on/off switches. This binding facilitates RNA polymerase activity and transcription of nearby genes.

What is the difference between an activator and an inducer?

Activators bind to the promoter to enhance the binding of RNA polymerase. Inducer molecules can increase transcription either by inactivating repressors or by activating activator proteins.

What does an activator do enzyme?

Enzyme activators are molecules that bind to enzymes and increase their activity. They are the opposite of enzyme inhibitors. These molecules are often involved in the allosteric regulation of enzymes in the control of metabolism.

How do you activate enzymes?

Enzyme activation can be accelerated through biochemical modification of the enzyme (i.e., phosphorylation) or through low molecular weight positive modulators. Just as with agonists of receptors, it is theoretically possible to bind molecules to enzymes to increase catalysis (enzyme activators).

Is Coenzyme A enzyme activator?

Coenzymes participate in catalysis when they bind to the active site of the enzyme (called apoenzyme) and subsequently form the active enzyme (called holoenzyme). Although coenzymes activate enzymes they are not considered as substrates of the reaction.

What are known as inhibitors?

a : an agent that slows or interferes with a chemical action. b : a substance that reduces or suppresses the activity of another substance (such as an enzyme)

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