What kind of therapy is Neulasta?

Neulasta® (pegfilgrastim) is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non‑myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low white blood cell count.

What is another name for Neulasta?

Neulasta is the trade name for pegfilgrastim. G-CSF is another name for pegfilgrastim. In some cases, health care professionals may use the trade name neulasta or other names G-CSF when referring to the generic drug name pegfilgrastim.

What is the meaning of Neulasta?

Listen to pronunciation. (noo-LA-stuh) A drug that is a form of filgrastim and is used to prevent infection in adults and children with neutropenia (a lower-than-normal number of white blood cells) caused by some types of chemotherapy.

What does Neulasta do to your body?

Neulasta (pegfilgrastim) is a colony-stimulating factor, a man-made form of a protein that stimulates the growth of white blood cells, used to decrease the incidence of infection, by treating neutropenia, a lack of certain white blood cells caused by receiving cancer chemotherapy.

What category of immunotherapy is pegfilgrastim?

Pegfilgrastim is in a class of medications called colony stimulating factors.

What are the long term side effects of Neulasta?

  • aortitis, which is inflammation in your aorta (the main heart artery)
  • capillary leak syndrome, which is a condition that involves tiny blood vessels leaking.
  • leukocytosis, which is an increased level of a type of white blood cell called leukocytes.
  • allergic reaction.

Why does Neulasta have to be given 24 hours after chemo?

This medication is usually given at least 24 hours after chemotherapy to stimulate the growth of new, healthy, white blood cells (WBC). Pegfilgrastim is a longer acting form of filgrastim and the manufacturer recommends that it should not be given within 14 days prior to chemotherapy.

How long does bone pain from Neulasta last?

The duration of bone pain from Neulasta is usually 2 to 4 days. Over-the-counter (OTC) medications are usually effective in preventing or relieving bone pain from Neulasta. Some examples of these drugs include: acetaminophen (Tylenol)

When should you not give Neulasta?

This medicine should not be given within 14 days before or 24 hours after you receive chemotherapy. Neulasta is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

Do all chemo patients get Neulasta?

Both the American Society of Clinical Oncology and the National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology recommend the Neulasta injection with every chemo cycle to guard against a serious infection manifested by a high fever called febrile neutropenia.

How much does a shot of Neulasta cost?

As of 08/18/2021 the list price for Neulasta® is $6,417.99* per dose. Neulasta® is a single dose administered once per chemotherapy cycle. Most patients do not pay the list price.

When is Neulasta most effective?

For the Neulasta to have its best effect it needs to go into the body 24 to 72 hours after chemotherapy.

What helps with bone pain from Neulasta?

Your doctor may prescribe a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen or naproxen to treat bone pain caused by Neulasta. Neulasta helps the body make more white blood cells by stimulating the immune system, which also creates histamines.

Why do you take Claritin with Neulasta?

The reason why Claritin (loratadine) is taken with Neulasta (pegfilgrastim) is to reduce bone pain, which is a very common side effect of Neulasta.

Why do chemo patients take Claritin?

We sometimes use loratadine (Claritin) to treat bone pain in patients receiving white blood cell growth factors. How does this work? White blood cell growth factors are used in the prevention and treatment of febrile neutropenia in patients receiving myelosuppressive chemotherapy.

Can Neulasta cause blood clots?

Tell your healthcare provider if you have unusual bleeding or bruising during treatment with Neulasta. This could be a sign of decreased platelet counts, which may reduce the ability of your blood to clot. Capillary Leak Syndrome. Neulasta can cause fluid to leak from blood vessels into your body’s tissues.

Does Neulasta affect platelets?

About: Pegfilgrastim (Neulasta®) Pegfilgrastim is a type of colony stimulating factor, which is a group of medications that stimulate the production and function of blood cells, including white blood cells, red blood cells and platelets.

What happens if you don’t take Neulasta?

Some patients find it hard to return to their physician the next day to receive Neulasta®, and missing a dose of Neulasta® can increase the risk of febrile neutropenia. With Onpro®, patients can receive Neulasta® at home so they don’t have to go back to the doctor on the day after chemo.

What is Red Devil chemo?

The chemotherapy (“chemo”) drug “The Red Devil” is doxorubicin (Adriamycin). It is an intravenous cancer medicine with a clear, bright red color, which is how it got its nickname.

Do you ever fully recover from chemotherapy?

If you were treated with certain types of chemotherapy, you can also have many of the same problems. Some problems go away after treatment. Others last a long time, while some may never go away. Some problems may develop months or years after your treatment has ended.

Does chemo affect your teeth?

Chemotherapy and radiation therapy may cause changes in the lining of the mouth and the salivary glands, which make saliva. This can upset the healthy balance of bacteria. These changes may lead to mouth sores, infections, and tooth decay.

How do you rebuild white blood cells after chemo?

Sometimes they are given antibiotics at this time to help prevent the development of a severe infection. The only treatment that has been proved to increase the number of white blood cells after chemotherapy is an injectable medicine that stimulates the bone marrow to make white blood cells faster.

How long does it take for white blood cells to increase after chemo?

Your neutrophil count then starts to rise again. This is because your bone marrow restarts normal production of neutrophils. But it may take 3 to 4 weeks to reach a normal level again. When your neutrophil level returns to normal, you are ready for the next round of chemotherapy.

How many rounds of chemo can a person have?

During a course of treatment, you usually have around 4 to 8 cycles of treatment. A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover.

Why is Neulasta so painful?

Neulasta stimulates your immune system into producing more white blood cells, which also leads to more histamine being created. And the release of histamine has been linked to bone marrow swelling and pain.

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